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Bio Active Care ®

Bio Active Care

Background, Problem & Needs:

Bio Active Care ® is a revolutionary medical device for chronic wounds treatment.

Chronic wounds do not heal, or heal slowly, because an underlying defect impedes local blood flow to the wound site and hinders the body’s natural wound healing processes. These types of wounds may never heal, or take years to heal, causing patients severe emotional and physical stress and creating a significant financial burden on patients and the whole healthcare system and in addition could eventually lead to wound infection, necrosis and finally - amputation of limbs.

Patients suffering from chronic wounds, experience severe damage to their health, severe pain, drowsiness (bad smell from the wound) and severe impairment of quality of life.


       Several factors can contribute to chronic wounds, including


  • Diabetes mellitus

  • Continued pressure

  • Poor circulation

  • Neuropathy

  • Difficulty moving

  • Systemic illnesses

  • Age

  • Repeated traum

      Chronic Wounds: There are 3 main types of chronic wounds:

  • Diabetic Ulcers

  • Venous and Arterial Ulcers

  • Pressure Ulcers

     Additional applications and treatments - NOT ONLY Chronic wounds:

  • Acceleration of wound recovery process (post operative, injuries, etc.)

  • Pilonidal Sinus

  • Fissure & Anal Fistula

  • Wound after Stoma removal

  • Preparation for skin transplant

  • Internal wounds

  • Any non-healing wound

    The Solution: Using Bio Active Care ® to Treat Chronic Wounds


Bio Active Care® is the first wound care product that enables health care providers to produce - in real time - in vitro blood clots from a patient’s whole blood. This innovative solution brings the patient’s blood to the site of the chronic wound to initiate and support the body's natural healing process.

Our general approach when treating with , is to bypass the problem of low or non-existing blood flow in the wound (the main cause of chronic wounds), by creating and applying an external blood clot from the patient’s own blood, outside and over the wound.

Once applied, the blood clot tissue serves as a protective covering and supports wound healing processes which naturally occur in the patient's body.

The Challenge of Treating Chronic Wounds - including diabetic ulcers, venous and arterial ulcers, and pressure ulcers, is that the wound often doesn’t heal or heal slowly because an underlying defect is impeding blood flow to the wound site. This lack of blood prevents the body from going through its natural wound healing processes.

Bio Active Care® technology is innovating the way we treat chronic wounds by managing each stage of the wound healing process.


    How Bio Active Care ®  Works:

Human skin, when injured, can repair itself to restore tissue integrity and heal the wound.

This wound healing involves 4 overlapping process, beginning immediately after injury:











The body works to stop the bleeding and start the healing process by activating a coagulation cascade. A fibrin blood clot forms that plugs severed blood vessels and fills in tissue discontinuity at the wound site.











During this phase, white blood cells and macrophages enter the wound to destroy bacteria and remove debris. The blood clot creates a fibrin scaffold that serves as a protective, provisional extracellular matrix (ECM) containing cytokines and growth factors (interleukin, transforming growth factor-β, platelet-derived growth factor, and vascular endothelial growth factor, among others) that facilitate tissue repair.










The blood clot recruits endothelial cells and fibroblasts to synthesize a permanent ECM.

The focus is filling and covering the wound.











The blood clot dries out and becomes a protective scab. Under the scab, tissue remodeling takes place undisturbed. The fibrin is replaced by fibronectin and hyaluronan, and the scab falls off to reveal a collagenous scar.


For patients that suffers from chronic wound the describes process does not happen because of the blood flow problem.

By using and creating the external blood clot, we trick the body to think there is a new and fresh wound (Acute wound) and generate the healing process as described above.

Basically, we push and promote the patient’s system to renew the healing process.


       Bio Active Care ® Advantages:

  • Using the patient’s own blood.

  • Initiates and moderates the healing process.

  • Promotes vascular growth.

  • Releases growth factors.

  • Attracts macrophages.

  • Acts as a scaffold.

  • Fight's infections.

  • Faster healing.

  • Remains active on the wound for prolonged periods (7 days).

  • Advanced biologic wound care to untreated chronic ulcers

  • Effective healing and minimally nursing time allow significant cost reduction.

      Bio Active Care ® Outcome:

  • Solution to non-healing wounds.

  • Reduced pain.

  • Reduced healing time.

  • Reduced nursing visits.

  • Reduced cost.


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